Since I have been losing my weekly pick-em pool at an almost impossible pace, this week I have resorted to my method from 15 years ago: Using the Sagarin Predictor ratings. I won a pretty penny with it back then, so let's see how it goes the rest of this season.
According to this method, the two biggest locks this week are Chicago laying the 3.5, and Detroit giving the 6.5. These are spreads from my pool, your spreads may vary.
In honor of Fausch, I think this thread should be for everybody's MasterLock Locks of the Century. No set schedule. Just post one when you have a CAN'T MISS.